Protect the Cavities, Please!

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2 By the end of his life, Armand Hammer, the prominent industrialist, had alienated virtually all of his friend s and family, driven his corporation into financial ruin, and tainted his public reputation. Nevertheless, he seemed quite pleased with himself: "There has never been anyone like me, and my likes will never be seen again"; "The brilliance of my mind can only be described as dazzling. ...

Please Print Clearly

The Boeing 777: no Chainsaw Massacres, please!

Iterative life cycle models have become popular in software engineering, e.g. in agile development. In contrast, the waterfall model appears to prevail in manufacturing engineering disciplines. This includes aircraft engineering and Boeing’s project for developing its most recent passenger aircraft, the 777. The paper walks through the phases of the 777’s development and compares this process t...

More data, please!

Witwer (1 ) observes in his review of miRNA studies that “data submission was reported at publication for 40% of all articles.” Sadly, the problem of poor data reporting is neither new nor restricted to miRNA data. Poor access to data motivated the 2001 MIAME (minimum information about a microarray experiment) standards in the first place (2 ). In 2008, Ochsner et al. (3 ) reviewed microarray s...

Next In Line, Please!

Inlining is an important optimization that can lead to significant runtime improvements. When deciding whether or not to inline a method call, a virtual machine has to weigh an increase in compile time against the expected decrease in program time. To estimate the latter, however, state-of-the-art heuristics only use information local to the call-site in question. But inlining is a powerful ena...